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波士顿波多黎各裔健康研究:波多黎各成年人健康差异的纵向队列研究:挑战与机遇。

The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities.

机构信息

USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA.

出版信息

BMC Public Health. 2010 Mar 1;10:107. doi: 10.1186/1471-2458-10-107.

Abstract

BACKGROUND

The Boston Puerto Rican Health Study is an ongoing longitudinal cohort study designed to examine the role of psychosocial stress on presence and development of allostatic load and health outcomes in Puerto Ricans, and potential modification by nutritional status, genetic variation, and social support.

METHODS

Self-identified Puerto Ricans, aged 45-75 years and residing in the Boston, MA metro area, were recruited through door-to-door enumeration and community approaches. Participants completed a comprehensive set of questionnaires and tests. Blood, urine and salivary samples were extracted for biomarker and genetic analysis. Measurements are repeated at a two-year follow-up.

RESULTS

A total of 1500 eligible participants completed baseline measurements, with nearly 80% two-year follow-up retention. The majority of the cohort is female (70%), and many have less than 8th grade education (48%), and fall below the poverty level (59%). Baseline prevalence of health conditions is high for this age range: considerable physical (26%) and cognitive (7%) impairment, obesity (57%), type 2 diabetes (40%), hypertension (69%), arthritis (50%) and depressive symptomatology (60%).

CONCLUSIONS

The enrollment of minority groups presents unique challenges. This report highlights approaches to working with difficult to reach populations, and describes some of the health issues and needs of Puerto Rican older adults. These results may inform future studies and interventions aiming to improve the health of this and similar communities.

摘要

背景

波士顿波多黎各健康研究是一项正在进行的纵向队列研究,旨在研究心理社会应激对波多黎各人群的应激反应和健康结果的发生和发展的作用,以及营养状况、遗传变异和社会支持的潜在调节作用。

方法

通过挨家挨户的普查和社区方法,招募自我认同为波多黎各人、年龄在 45-75 岁之间、居住在马萨诸塞州波士顿都会区的参与者。参与者完成了一套全面的问卷和测试。提取血液、尿液和唾液样本进行生物标志物和遗传分析。测量结果在两年的随访中重复。

结果

共有 1500 名符合条件的参与者完成了基线测量,其中近 80%的人进行了两年的随访。该队列的大多数参与者为女性(70%),许多人教育程度低于 8 年级(48%),且收入低于贫困线(59%)。对于这个年龄段来说,基线健康状况的患病率很高:相当数量的人存在身体(26%)和认知(7%)障碍、肥胖(57%)、2 型糖尿病(40%)、高血压(69%)、关节炎(50%)和抑郁症状(60%)。

结论

招募少数群体带来了独特的挑战。本报告重点介绍了针对难以接触人群的工作方法,并描述了波多黎各老年人的一些健康问题和需求。这些结果可能为旨在改善这一社区和类似社区健康的未来研究和干预措施提供信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/993a/2848197/eec3611a87fa/1471-2458-10-107-1.jpg

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