Liu Wei, Xiao Li-ping, Li Yun, Wang Xin-qiong, Xu Chun-di
Department of Pediatrics, Shanghai Ruijin Hospital Affiliated to School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.
Zhonghua Er Ke Za Zhi. 2009 Dec;47(12):917-21.
To determine the prevalence of functional gastrointestinal disorders in children in Shanghai.
This study was conducted on the infants and young children who were below 24 months of age recruited consecutively from April 2008 to June 2008 from the 12 communities in Minhang district in Shanghai. The questionnaire on gastrointestinal symptoms and growth was sent to 5030 children < 24 months old. The age distribution of the 5030 children was: < 6 months: 1922 infants (38.2%), 6 - < 12 months: 1933 (38.4%) infants; 12 - < 18 months: 811 (16.1%) children; 18 - < 24 months: 364 (7.2%) children.
Among the 5030 children, 1909 had gastrointestinal disorders (38.0%). There was no significant difference in the rate of the disorders between sexes (P = 0.06). Regurgitation was found in 899 (17.9%) infants/children, constipation in 690 (13.7%), 619 (12.3%) infants/children suffered from diarrhea and only 71 (1.4%) suffered from colic. The incidence of gastrointestinal disorders was significantly different among different age groups. The incidence of constipation and regurgitation decreased and the incidence of diarrhea increased with growth (P < 0.01). Infants growth parameters in the group with gastrointestinal disorders especially in those with regurgitation were lower than those without gastrointestinal disorders, the difference is statistically significant. The hospital visit rate of infants with diarrhea was 62.68%, which was higher than the rate of the other three symptoms (4.45% - 16.90%).
Gastrointestinal disorders are common in infants and young children in Shanghai and may have a great impact on growth. Early management could relieve the disorders and ensure infants to get normal growth and development.
确定上海儿童功能性胃肠病的患病率。
本研究对2008年4月至2008年6月从上海闵行区12个社区连续招募的24个月以下婴幼儿进行。向5030名24个月以下儿童发放了关于胃肠道症状和生长情况的问卷。5030名儿童的年龄分布为:6个月以下:1922名婴儿(38.2%),6至12个月:1933名(38.4%)婴儿;12至18个月:811名(16.1%)儿童;18至24个月:364名(7.2%)儿童。
在5030名儿童中,1909名患有胃肠疾病(38.0%)。疾病发生率在性别之间无显著差异(P = 0.06)。899名(17.9%)婴幼儿出现反流,690名(13.7%)出现便秘,619名(12.3%)婴幼儿患有腹泻,仅71名(1.4%)患有腹绞痛。胃肠疾病的发生率在不同年龄组之间存在显著差异。便秘和反流的发生率随生长而降低,腹泻的发生率随生长而升高(P < 0.01)。患有胃肠疾病的组尤其是反流组婴幼儿的生长参数低于无胃肠疾病的组,差异具有统计学意义。腹泻婴幼儿的就诊率为62.68%,高于其他三种症状的就诊率(4.45% - 16.90%)。
胃肠疾病在上海婴幼儿中很常见,可能对生长有很大影响。早期管理可以缓解这些疾病,确保婴幼儿正常生长发育。