在流行病学研究中匹配还是不匹配——相同的结局但效力更小。
To match or not to match in epidemiological studies--same outcome but less power.
机构信息
Department of Medical and Health Sciences, Community Medicine, Linköping University, SE-58183 Linköping, Sweden.
出版信息
Int J Environ Res Public Health. 2010 Jan;7(1):325-32. doi: 10.3390/ijerph7010325. Epub 2010 Jan 26.
Abstract
This study aimed to analyze the possible resemblance or difference in outcome in a case-control study of quality of life for IBS patients compared to controls free from the disease, when a matching procedure for age and sex was applied for the control group compared to when all participating subjects were included in the control group. The main result was that almost the same and identical results were found irrespective of whether matching or not matching was applied in this epidemiological case-control study. The matching procedure however, slightly diminished the statistical power of the results.
摘要
本研究旨在分析在一项针对 IBS 患者生活质量的病例对照研究中，当对对照组进行年龄和性别匹配时与不对对照组进行年龄和性别匹配时，病例组和对照组之间的结果是否存在相似或不同。主要结果是，无论在这项流行病学病例对照研究中是否进行匹配，几乎都得到了相同的结果。然而，匹配过程略微降低了结果的统计效力。
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