Department of Psychiatry, Medical University of South Carolina, Mt Pleasant, SC 29466, USA.
Arch Clin Neuropsychol. 2010 May;25(3):157-73. doi: 10.1093/arclin/acq014. Epub 2010 Mar 2.
Attention deficit hyperactivity disorder (ADHD) is associated with deficits in executive functioning (EF). ADHD in adults is also associated with impairments in major life activities, particularly occupational functioning. We investigated the extent to which EF deficits assessed by both tests and self-ratings contributed to the degree of impairment in 11 measures involving self-reported occupational problems, employer reported workplace adjustment, and clinician rated occupational adjustment. Three groups of adults were recruited as a function of their severity of ADHD: ADHD diagnosis (n = 146), clinical controls self-referring for ADHD but not diagnosed with it (n = 97), and community controls (n = 109). Groups were combined and regression analyses revealed that self-ratings of EF were significantly predictive of impairments in all 11 measures of occupational adjustment. Although several tests of EF also did so, they contributed substantially less than did the EF ratings, particularly when analyzed jointly with the ratings. We conclude that EF deficits contribute to the impairments in occupational functioning that occur in conjunction with adult ADHD. Ratings of EF in daily life contribute more to such impairments than do EF tests, perhaps because, as we hypothesize, each assesses a different level in the hierarchical organization of EF as a meta-construct.
注意缺陷多动障碍(ADHD)与执行功能(EF)缺陷有关。成人 ADHD 也与主要生活活动,特别是职业功能的损伤有关。我们研究了通过测试和自我评估评估的 EF 缺陷在多大程度上导致 11 项自我报告职业问题、雇主报告的工作场所调整和临床医生评定的职业调整的损害程度。根据 ADHD 的严重程度招募了三组成年人:ADHD 诊断组(n = 146)、临床对照组(n = 97),他们因 ADHD 而自我转诊但未被诊断为 ADHD,以及社区对照组(n = 109)。将这些组进行合并,并进行回归分析显示,EF 的自我评估与所有 11 项职业调整的损伤都有显著的相关性。虽然一些 EF 测试也如此,但它们的贡献明显小于 EF 评级,特别是在与评级联合分析时。我们得出结论,EF 缺陷导致与成人 ADHD 相关的职业功能障碍。日常生活中的 EF 评级对这种损伤的贡献比 EF 测试更大,这可能是因为,正如我们假设的那样,每个测试都在 EF 作为元结构的分层组织中的不同层次上进行评估。