Department of Orthopedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16 Chuo-ku, Sapporo, Hokkaido 060-8543, Japan.
Int J Clin Oncol. 2010 Aug;15(4):416-9. doi: 10.1007/s10147-010-0048-7. Epub 2010 Mar 4.
Giant cell tumor of the sacrum is extremely difficult to manage. Standard treatments, including surgery and radiation, are associated with significant complications and recurrence rates. In this manuscript, we report an early clinical result of a case of giant cell tumor of the sacrum successfully managed with selective arterial embolization. A 56-year-old woman underwent selective embolization for management of giant cell tumor of the sacrum. Radiologically, massive shrinkage of the extraosseous mass and increased peripheral ossification were obvious. Clinically, rapid pain relief was achieved and gait disability recovered. At final follow-up 28 months after completion of treatment, she retained normal activity in daily life. We stress the effectiveness of selective arterial embolization as a less invasive and less complicated primary treatment of giant cell tumors of the sacrum.
骶骨巨细胞瘤极难治疗。包括手术和放疗在内的标准治疗方法与严重的并发症和复发率相关。在本病例报告中，我们报道了一例骶骨巨细胞瘤患者成功接受选择性动脉栓塞治疗的早期临床结果。一名 56 岁女性因骶骨巨细胞瘤接受选择性栓塞治疗。影像学上，骨外肿块明显缩小，周围骨化增加。临床上，疼痛迅速缓解，步态障碍恢复。治疗结束后 28 个月的最终随访时，她保留了日常生活的正常活动。我们强调了选择性动脉栓塞作为一种侵袭性较小、更简单的骶骨巨细胞瘤的主要治疗方法的有效性。
