Ingall T J, McLeod J G
Department of Neurology, Royal North Shore Hospital, St Leonards, NSW, Australia.
J Neurol Neurosurg Psychiatry. 1991 Feb;54(2):162-4. doi: 10.1136/jnnp.54.2.162.
Autonomic function studies were performed on 15 patients with Friedreich's ataxia, and the results compared with those of 76 healthy subjects. There was an increase in resting supine heart rate, attributed to cardiac abnormalities. Other tests of sympathetic and parasympathetic function were normal. The normal autonomic function studies are consistent with the pathological findings of degeneration predominantly of large diameter myelinated fibres with sparing of small myelinated and unmyelinated fibres.
对15例弗里德赖希共济失调患者进行了自主神经功能研究，并将结果与76名健康受试者的结果进行了比较。静息仰卧心率增加，归因于心脏异常。交感神经和副交感神经功能的其他测试均正常。自主神经功能研究结果正常与病理结果一致，即主要是大直径有髓纤维变性，而小直径有髓纤维和无髓纤维未受影响。
