Department for Environment, Food and Rural Affairs, Food and Environment Research Agency, York YO411LZ, UK.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Apr;27(4):530-45. doi: 10.1080/19440040903476590.
The analysis of 252 food samples (UK-produced and imported) purchased from a variety of retail outlets in the UK was undertaken for the presence of perfluorooctanesulphonic acid (PFOS), perfluorooctanoic acid (PFOA) and nine other perfluorocompounds (PFCs). A limit of quantification (LOQ) of 1 microg/kg was achieved for all target analytes, in all samples. Standard addition was used for quantification of PFC levels. All 11 of the targeted PFCs were detected in 75 individual food items. In 70% of the samples, including all meat other than offal, none of the analytes were present above the LOD. The highest levels found were 59 microg/kg perfluorooctanesulphonic acid (PFOS) and 63 microg/kg total PFCs (SigmaPFCs) in an eel sample, and 40 microg/kg PFOS (62 microg/kg SigmaPFCs) in a whitebait sample. The highest level in an offal sample was 10 microg/kg, in a wild roe deer liver. There were six samples with SigmaPFCs >15 microg/kg (fish, shellfish, crustaceans), a further seven samples with SigmaPFCs ranging 11-15 microg/kg (including a liver), nine with SigmaPFCs ranging 6-10 microg/kg (fish and livers), 31 with SigmaPFCs in the range 2-5 microg/kg (including kidneys, popcorn and processed peas) and a further 22 with SigmaPFCs close to the LOD of 1 microg/kg (including eggs and potatoes). These concentrations indicate that UK consumers are being exposed to a low level of PFC contamination from food. The estimated upper bound dietary intake of 10 ng/kg bodyweight (bw)/day of PFOS for average adult consumers is well below the 0.15 microg (150 ng)/kg bw tolerable daily intake (TDI) set by the European Food Safety Authority. The lower bound adult dietary intake estimate of 1 ng/kg bw/day is similar to estimates undertaken and reported in countries such as Canada, Germany and Spain.
对从英国各种零售商店购买的 252 种食品（英国生产和进口）进行了分析，以检测全氟辛烷磺酸（PFOS）、全氟辛酸（PFOA）和其他 9 种全氟化合物（PFCs）的存在。所有目标分析物的定量限（LOQ）均达到 1μg/kg，所有样品均如此。采用标准添加法对 PFC 水平进行定量。在所分析的 11 种目标 PFCs 中，有 75 种单独食品中都检测到了这些物质。在 70%的样品中，包括所有除了动物内脏之外的肉类，均未检出任何低于检测限的分析物。在鳗鱼样本中，全氟辛烷磺酸（PFOS）的最高检出浓度为 59μg/kg，全氟化合物（SigmaPFCs）总浓度为 63μg/kg；在小白鱼样本中，PFOS 的最高检出浓度为 40μg/kg，SigmaPFCs 总浓度为 62μg/kg。在野生动物鹿肝样本中，检出的全氟辛烷磺酸浓度最高，为 10μg/kg。有 6 个样本的 SigmaPFCs 浓度大于 15μg/kg（鱼类、贝类、甲壳类），另有 7 个样本的 SigmaPFCs 浓度在 11-15μg/kg 之间（包括 1 个肝脏样本），9 个样本的 SigmaPFCs 浓度在 6-10μg/kg 之间（鱼类和肝脏），31 个样本的 SigmaPFCs 浓度在 2-5μg/kg 之间（包括肾脏、爆米花和加工豌豆），另有 22 个样本的 SigmaPFCs 浓度接近检测限 1μg/kg（包括鸡蛋和土豆）。这些浓度表明，英国消费者正从食物中接触到低水平的 PFC 污染。对于普通成年消费者，估计每日最高摄入 10ng/kg 体重（bw）的 PFOS 为 10ng/kg bw，远低于欧洲食品安全局设定的 0.15μg（150ng）/kg bw 可耐受每日摄入量（TDI）。成人每日最低摄入量估计值为 1ng/kg bw，与加拿大、德国和西班牙等国家开展的研究和报告的估计值相似。
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