口服氯胺酮用于大疱性表皮松解症婴儿换药时的镇痛：1例报告

The use of oral ketamine for analgesia with dressing change in an infant with epidermolysis bullosa: report of a case.

作者信息

Saroyan John M, Tresgallo Mary E, Farkouh Christiana, Morel Kimberly D, Schechter William S

机构信息

Division of Pediatric Pain Medicine, Symptom Management and Palliative Care, Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York 10032, USA.

出版信息

Pediatr Dermatol. 2009 Nov-Dec;26(6):764-6. doi: 10.1111/j.1525-1470.2009.01036.x.

DOI:10.1111/j.1525-1470.2009.01036.x

PMID:20199468

Abstract

Epidermolysis bullosa (EB) describes a spectrum of disease from occasional bullae and callus formation to a debilitating life-threatening condition. In this study, we report the use of intravenous ketamine given orally to an infant with a phenotypically severe form of EB simplex, Dowling-Meara subtype, to achieve analgesia during painful dressing changes.

摘要

大疱性表皮松解症（EB）描述了一系列疾病，从偶尔出现的水疱和胼胝形成到危及生命的衰弱状况。在本研究中，我们报告了对一名患有表型严重的单纯型EB（Dowling-Meara亚型）的婴儿口服静脉用氯胺酮，以在痛苦的换药过程中实现镇痛。