Department of Psychiatry, National University of Ireland, Galway, Ireland.
Acta Psychiatr Scand. 2011 Jan;123(1):21-7. doi: 10.1111/j.1600-0447.2010.01546.x.
To explore the relationship between cannabis use and self-reported dimensions of psychosis in a population of university students presenting for any reason to primary care.
One thousand and forty-nine students attending the Student Health Unit, National University of Ireland, Galway, completed self-report questionnaires on alcohol and substance misuse, non-clinical dimensions of psychosis [Community Assessment of Psychic Experiences (CAPE)], anxiety and depression [Hospital Anxiety and Depression Scale (HADS)]. Association of cannabis use with psychiatric symptoms was explored whilst controlling for confounds.
More frequent cannabis use was independently associated with greater intensity of positive, negative and depressive psychotic symptoms. The earlier the age of onset of cannabis use, the more positive psychotic symptoms were reported.
These findings support the hypotheses that cannabis use increases the risk of developing psychotic symptoms and that this risk is further increased in those individuals who use cannabis more heavily and commence it at a younger age.
在因任何原因前往初级保健的大学生人群中，探索大麻使用与自我报告的精神病维度之间的关系。
在戈尔韦国立爱尔兰大学的学生健康中心，1049 名学生完成了关于酒精和物质滥用、非临床精神病维度[社区心理体验评估（CAPE）]、焦虑和抑郁[医院焦虑和抑郁量表（HADS）]的自我报告问卷。在控制混杂因素的情况下，探讨了大麻使用与精神症状之间的关联。
更频繁的大麻使用与更强烈的阳性、阴性和抑郁性精神病症状独立相关。大麻使用的发病年龄越早，报告的阳性精神病症状就越多。
这些发现支持了以下假设，即大麻使用增加了出现精神病症状的风险，并且在那些更频繁使用大麻且发病年龄更早的个体中，这种风险进一步增加。
