Department of Geriatric Behavioral Neurology, Tohoku University Graduate School of Medicine, 2-1, Seiryo-machi, Aoba-ku, 980-8575 Sendai, Miyagi, Japan.
Arch Gerontol Geriatr. 2011 Jan-Feb;52(1):75-8. doi: 10.1016/j.archger.2010.02.003. Epub 2010 Mar 3.
In 1997 we examined the prevalence of dementia among the Japanese elderly immigrants living in the São Paulo metropolitan area (n=166). Herein, we followed up on these subjects for causes of death and dementia incidence. We were able to contact 108 subjects: 54 were already dead. The most common cause of death was cardiac disease. For dementia, 31.6% of the dead subjects were found to have developed dementia before they died, and 20.8 % of the living subjects were demented. As for the baseline the clinical dementia rating (CDR), 20.8 % of CDR 0 and 50.0 % of CDR 0.5 subjects developed dementia in the dead group; whereas in the living group, 23.9 % of CDR 0 and 52.6 % of CDR 0.5 developed dementia. As a whole, the incidence was 34.2 ‰ per 1000 person-years. Cardiac disease as the most common cause of death was probably due to the higher prevalence of diabetes mellitus. Compared with the previous study, the lower incidence of dementia from the CDR 0.5 group may have been due to a higher mortality rate. This is the first study on the incidence of dementia in elderly Japanese immigrants in Brazil.
1997 年，我们调查了居住在圣保罗大都市区的日本老年移民中的痴呆患病率（n=166）。在此，我们对这些受试者进行了死因和痴呆发病率的随访。我们能够联系到 108 名受试者：其中 54 人已经死亡。最常见的死因是心脏病。对于痴呆症，死亡受试者中有 31.6%在死亡前被诊断为痴呆症，而存活受试者中有 20.8%患有痴呆症。至于基线时的临床痴呆评定量表（CDR），死亡组中 CDR0 的 20.8%和 CDR0.5 的 50.0%的受试者发展为痴呆症；而在存活组中，CDR0 的 23.9%和 CDR0.5 的 52.6%发展为痴呆症。总的来说，发病率为每 1000 人年 34.2‰。心脏病作为最常见的死因可能是由于糖尿病的患病率较高。与之前的研究相比，CDR0.5 组的痴呆发病率较低，可能是由于死亡率较高。这是第一项关于巴西老年日本移民痴呆发病率的研究。
