Autophagy for the avoidance of degenerative, inflammatory, infectious, and neoplastic disease.
作者信息
Kroemer Guido, White Eileen
出版信息
Curr Opin Cell Biol. 2010 Apr;22(2):121-3. doi: 10.1016/j.ceb.2010.02.003. Epub 2010 Mar 2.
Abstract
摘要
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本文引用的文献
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Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol.自噬介导了亚精胺和白藜芦醇对寿命的药理学延长作用。
Aging (Albany NY). 2009 Dec 23;1(12):961-70. doi: 10.18632/aging.100110.
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HIF-1: upstream and downstream of cancer metabolism.缺氧诱导因子 1：癌症代谢的上下游。
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The double-edged sword of autophagy modulation in cancer.癌症中自噬调节的双刃剑
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Autophagy suppresses tumorigenesis through elimination of p62.自噬通过清除p62抑制肿瘤发生。
Cell. 2009 Jun 12;137(6):1062-75. doi: 10.1016/j.cell.2009.03.048.
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Autophagy regulates lipid metabolism.自噬调节脂质代谢。
Nature. 2009 Apr 30;458(7242):1131-5. doi: 10.1038/nature07976. Epub 2009 Apr 1.
6
Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.自噬抑制会损害泛素-蛋白酶体途径底物的降解。
Mol Cell. 2009 Feb 27;33(4):517-27. doi: 10.1016/j.molcel.2009.01.021.
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Role of BNIP3 and NIX in cell death, autophagy, and mitophagy.BNIP3和NIX在细胞死亡、自噬及线粒体自噬中的作用。
Cell Death Differ. 2009 Jul;16(7):939-46. doi: 10.1038/cdd.2009.16. Epub 2009 Feb 20.
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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.自噬及自噬基因Atg16l1在小鼠和人类肠道潘氏细胞中的关键作用。
Nature. 2008 Nov 13;456(7219):259-63. doi: 10.1038/nature07416. Epub 2008 Oct 5.
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Autophagy is essential for preimplantation development of mouse embryos.自噬对于小鼠胚胎植入前发育至关重要。
Science. 2008 Jul 4;321(5885):117-20. doi: 10.1126/science.1154822.
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Autophagy in the pathogenesis of disease.自噬在疾病发病机制中的作用
Cell. 2008 Jan 11;132(1):27-42. doi: 10.1016/j.cell.2007.12.018.
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