Centro de Investigaciones de Plagas e Insecticidas (CIPEIN, CITEFA-CONICET), Villa Martelli, Provincia de Buenos Aires, Argentina.
Pest Manag Sci. 2010 Jul;66(7):705-8. doi: 10.1002/ps.1931.
Triatoma infestans (Klug) is the major Chagas disease vector in the Southern Cone area of South America, and its chemical control is based on the use of pyrethroid insecticides. Resistance to deltamethrin in Salta Province, Argentina, has been detected in field populations since 2002, causing the failure of vector control campaigns in this disease-endemic area. The inheritance of deltamethrin resistance in T. infestans was evaluated through reciprocal crosses conducted between resistant and susceptible insects.
The response of the reciprocally mated insects' progeny to deltamethrin was intermediate between the highly resistant and the susceptible parent colonies. Lack of significant differences between the LD(50) and resistance ratios of the reciprocally mated insects indicated no sex linkage on this trait.
Bioassay results, in addition to degree of dominance calculations, suggest that the resistance to deltamethrin in T. infestans is controlled by semi-dominant, autosomally inherited factors.
布氏田鼠（Klug）是南美洲南部锥体地区的主要恰加斯病传播媒介，其化学控制基于拟除虫菊酯杀虫剂的使用。自 2002 年以来，在阿根廷萨尔塔省的田间种群中已经检测到对溴氰菊酯的抗药性，导致该疾病流行地区的媒介控制运动失败。通过在抗性和敏感昆虫之间进行正反交，评估了布氏田鼠对溴氰菊酯的抗药性遗传。
正反交配昆虫后代对溴氰菊酯的反应介于高度抗性和敏感亲本品系之间。互交昆虫的 LD（50）和抗性比值之间没有显著差异，表明该性状没有性连锁。
生物测定结果，除了显性度计算外，表明布氏田鼠对溴氰菊酯的抗性由半显性、常染色体遗传因子控制。
