Lin James S
Geriatric Research Education and Clinical Center, Atlanta Veterans Affairs Medical Center, Clairmont Road, Decatur Georgia 30033, USA.
J Med Case Rep. 2010 Jan 8;4:4. doi: 10.1186/1752-1947-4-4.
Hyperlipidemia is prevalent and is highly associated with coronary heart disease. Some patients are reluctant or opt not to take lipid-lowering prescription medications for fear of adverse drug reactions. There are currently few well-designed randomized controlled trials showing the possibility of reducing cholesterol using red yeast rice. Meanwhile, adverse effects have also been reported.
A 64-year-old Asian man was diagnosed with hyperlipidemia despite a healthy lifestyle. In addition to diet changes, the patient used red yeast rice and succeeded in lowering his level of serum lipids.
Based on this case and a review of current literature, in addition to therapeutic lifestyle change, red yeast rice may be a useful alternative treatment for primary hyperlipidemia in patients with low cardiac risk and who refuse to take any lipid-lowering prescription medication or who maybe be statin intolerant.However, primary care physicians must be aware of the potential side effects of taking red yeast rice.
高脂血症很常见,且与冠心病高度相关。一些患者因担心药物不良反应而不愿或选择不服用降脂处方药。目前很少有设计良好的随机对照试验表明使用红曲米降低胆固醇的可能性。同时,也有不良反应的报道。
一名64岁的亚洲男性尽管生活方式健康,但仍被诊断为高脂血症。除了改变饮食外,该患者使用红曲米并成功降低了血脂水平。
基于此病例及对当前文献的综述,除了治疗性生活方式改变外,红曲米对于心脏风险较低、拒绝服用任何降脂处方药或可能不耐受他汀类药物的原发性高脂血症患者可能是一种有用的替代治疗方法。然而,初级保健医生必须意识到服用红曲米的潜在副作用。