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希腊北部一家综合儿科诊所收治患儿的遗传疾病频率和健康保险覆盖情况。

Frequency of genetic diseases and health coverage of children requiring admission in a general pediatric clinic of northern Greece.

机构信息

Department of Genetics, Democritus University of Thrace Medical School, Dragana, Alexandroupolis 68100, Greece.

出版信息

Ital J Pediatr. 2010 Jan 26;36:9. doi: 10.1186/1824-7288-36-9.

DOI:10.1186/1824-7288-36-9
PMID:20205810
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2823766/
Abstract

BACKGROUND

In order to estimate the causes of pediatric morbidity in our area, with particular emphasis on diseases with a genetic background, we retrospectively categorized the admissions of all children hospitalized in the Department of Pediatrics of the University General Hospital of Alexandroupolis, in the area of Evros, Thrace, Greece over the three year period 2005-2007. Finally, in order to guide health care administrators to improve the delivery of pediatric health care services, we estimated the percentage of hospitalized children who were uninsured and the type of health insurance of those who had medical coverage.

PATIENTS AND METHODS

The causes of admission, as recorded in the medical records were categorized in terms of the major organ and/or system involved and/or the underlying pathology, with emphasis on diseases with a genetic background. Duplicate admissions, i.e., admissions of the same child for the same underlying disease were excluded. Additional information recorded was age, sex, and type of health insurance of all admitted children. Distribution of the causes of admission by study year was compared by chi-square. A p value < 0.05 was considered significant.

RESULTS

Over the study period, there were 4,947 admissions in 2,818 boys and 2,129 girls. Respiratory diseases were the most common accounting for 30%, while infectious diseases followed with 26.4%. The frequency of chromosomal abnormalities among the hospitalized children was only 0.06%. However, if we consider diseases with an underlying genetic background, this percentage rises to 5%. Approximately 10.3% of the admitted children had no health insurance.

CONCLUSIONS

The percentage of children hospitalized in our area due to a disease with an underlying genetic background was 5%. This percentage pertains to a Department of Pediatrics that has no inpatient subspecialty units and which is located within a General hospital, because hospitalizations for genetic diseases are more frequent in specialized pediatric hospitals, with competence in clinical genetics. The double figure of uninsured children is worrisome and dictates the need for governmental efforts for universal pediatric health coverage in our country.

摘要

背景

为了评估我们地区儿科发病率的原因,特别强调具有遗传背景的疾病,我们回顾性地对 2005 年至 2007 年期间在希腊色雷斯亚历山德鲁波利斯大学综合医院儿科住院的所有儿童的入院情况进行了分类。最后,为了指导医疗保健管理人员改善儿科医疗服务的提供,我们估计了未参保住院儿童的百分比以及有医疗保险的儿童的医疗保险类型。

患者和方法

根据主要器官和/或系统受累及/或潜在病理学,将病历中记录的入院原因进行分类,重点关注具有遗传背景的疾病。排除重复入院,即同一儿童因同一潜在疾病的入院。记录了所有入院儿童的年龄、性别和类型的健康保险。通过卡方检验比较各研究年度入院原因的分布。p 值<0.05 被认为有统计学意义。

结果

在研究期间,有 4947 例住院治疗,其中 2818 例为男孩,2129 例为女孩。呼吸系统疾病最常见,占 30%,其次是传染病,占 26.4%。住院儿童中染色体异常的频率仅为 0.06%。然而,如果我们考虑具有潜在遗传背景的疾病,这一比例上升到 5%。约 10.3%的住院儿童没有医疗保险。

结论

在我们地区,因潜在遗传背景疾病住院的儿童比例为 5%。这一比例适用于没有住院专科单位且位于综合医院内的儿科,因为遗传疾病的住院治疗更常见于具有临床遗传学专业知识的专门儿科医院。未参保儿童的比例令人担忧,这要求我们在我国努力实现全民儿童健康保险。

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