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[作为疫苗的猪传染性胃肠炎减毒病毒株的试验]

[Test of an attenuated viral strain of TGE as a vaccine].

作者信息

Kristov S, Karadzhov I, Tatarov G, Ignatov G, Khristova V

出版信息

Vet Med Nauki. 1977;14(6):3-10.

PMID:202064
Abstract

A live vaccine was produced using a local strain P of the virus of the transmissive gastroenteritis, arrenuated in cell cultures. The vaccinated pregnant sows had high-titer serum and colostrum virus-neutralizing antibodies. In the first days following farrowing there were in the colostrum ummunoglobulins of the Igg class that prevailed, however, IgA and IgM proved more effective in the virus-neutralizing test. Newborn pigs acquired passive immunity at about the 24th hour after the intake of colostrum. They withstood a challenge with a virulent virus.

摘要

使用一种在细胞培养中致弱的传染性胃肠炎病毒的本地毒株P生产了一种活疫苗。接种疫苗的怀孕母猪具有高滴度的血清和初乳病毒中和抗体。分娩后的头几天,初乳中以Igg类免疫球蛋白为主,然而,IgA和IgM在病毒中和试验中被证明更有效。新生仔猪在摄入初乳后约24小时获得被动免疫。它们经受住了强毒病毒的攻击。

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