Woods R D
Am J Vet Res. 1984 Sep;45(9):1726-9.
Three groups of pregnant sows were vaccinated at 8 and 2 weeks before parturition with tissue culture-adapted feline infectious peritonitis (FIP) virus, porcine transmissible gastroenteritis (TGE) small-plaque (SP) virus from a persistently infected cell line, or noninfected cell culture fluids (controls). Pigs nursing vaccinated sows were orally challenge exposed with virulent TGE virus when they were 1 to 3 days old. The morbidity of the nursing pigs was 48% in the SP-TGE group, 82% in the FIP group, and 93% in the controls. The survival rate among the nursing pigs was 77% in the SP-TGE groups, 48% in the FIP group, and 14% in the controls. Virus-neutralizing antibodies of immunoglobulin A were detected in colostrum and milk of the SP-TGE group, but not in the FIP or control groups.
将三组怀孕母猪在分娩前8周和2周时分别用适应组织培养的猫传染性腹膜炎（FIP）病毒、来自持续感染细胞系的猪传染性胃肠炎（TGE）小蚀斑（SP）病毒或未感染的细胞培养液（对照组）进行接种。哺乳接种过疫苗母猪的仔猪在1至3日龄时经口用强毒TGE病毒进行攻毒暴露。哺乳仔猪的发病率在SP-TGE组为48%，在FIP组为82%，在对照组为93%。哺乳仔猪的存活率在SP-TGE组为77%，在FIP组为48%，在对照组为14%。在SP-TGE组的初乳和乳汁中检测到免疫球蛋白A的病毒中和抗体，但在FIP组或对照组中未检测到。
