Eye Hospital University of Münster, Münster, Germany.
Ophthalmology. 2010 Apr;117(4):785-90. doi: 10.1016/j.ophtha.2009.12.016. Epub 2010 Mar 5.
First, to evaluate the anatomic success rates of scleral buckling surgery in the treatment of rhegmatogenous retinal detachment and possible differences in outcome depending on patients' refractive error and lens status. Second, to evaluate demographic characteristics of patients with retinal detachment to contribute to our knowledge of the epidemiology of this important and sight-threatening disease.
Retrospective interventional case series.
The Munster Study on Therapy Achievements in Retinal Detachment (MUSTARD) is one of the largest case series of patients with retinal detachment and their outcome after buckling surgery ever established, with 4325 subjects who underwent surgery between 1980 and 2001.
All 4325 patients with retinal detachment underwent scleral buckling surgery.
Complete anatomic attachment of the retina.
The overall success rate in all 4325 MUSTARD cases was 83.98%. The highest success rate was achieved in patients aged 51 to 60 years, with 86.72%. With regard to refractive error, success rates were highest in moderate myopes, that is, in 707 patients with a refractive error between -2.75 and -8.0 diopters (86.70%) and in 573 patients with mild myopia between -0.5 and -2.0 diopters (86.21%). The lens status did not play a significant role in outcome. In patients with nontrauma-related retinal detachment, success rates were 84.45% for phakic patients, 82.88% for pseudophakic patients, and 81.88% for aphakic patients. An epidemiologically surprising result was the lower than expected number of myopic individuals among patients with retinal detachment: Only approximately one quarter had myopia of -2.75 diopters or more. In phakic patients aged 51 to 80 years, only 16% were myopic.
Scleral buckling is an established and generally successful method for the treatment of retinal detachment. As our case series has demonstrated, myopia, aphakia, and pseudophakia do not constitute factors that might diminish the chances of success.
FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found after the references.
首先，评估巩膜扣带术治疗孔源性视网膜脱离的解剖成功率，并根据患者的屈光不正和晶状体状态评估结果的可能差异。其次，评估视网膜脱离患者的人口统计学特征，以增进我们对这一重要致盲性疾病的流行病学认识。
回顾性干预性病例系列研究。
Munster 视网膜脱离治疗疗效研究（MUSTARD）是最大的视网膜脱离患者及其巩膜扣带术后结果的病例系列之一，纳入了 1980 年至 2001 年间接受手术的 4325 名患者。
所有 4325 例视网膜脱离患者均行巩膜扣带术。
视网膜完全解剖复位。
4325 例 MUSTARD 病例的总体成功率为 83.98%。51 至 60 岁患者的成功率最高，为 86.72%。就屈光不正而言，中度近视患者（即 707 例屈光度在-2.75 至-8.0 屈光度之间和 573 例轻度近视患者[屈光度在-0.5 至-2.0 屈光度之间]的成功率最高，分别为 86.70%和 86.21%。晶状体状态对结果无显著影响。非外伤性视网膜脱离患者中，晶体在位患者的成功率为 84.45%，人工晶状体眼患者为 82.88%，无晶状体眼患者为 81.88%。结果出人意料的是，视网膜脱离患者中近视患者的比例低于预期：仅有约四分之一的患者近视程度达到-2.75 屈光度或更高。51 至 80 岁晶体在位患者中，近视者仅占 16%。
巩膜扣带术是治疗视网膜脱离的一种成熟且普遍有效的方法。正如我们的病例系列研究所示，近视、无晶状体和人工晶状体眼并非降低手术成功率的因素。
参考文献之后可能有专有或商业披露。
