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评估Accutrend GCT血糖仪和PTS CardioChek血糖仪用于测量猫的血液甘油三酯浓度的情况。

Assessment of the Accutrend GCT and PTS CardioChek meters to measure blood triglyceride concentrations in cats.

作者信息

Kluger Elissa K, Dhand Navneet K, Baral Randolph M, Snow David H, Malik Richard, Govendir Merran

机构信息

Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia.

出版信息

J Feline Med Surg. 2010 Jun;12(6):458-65. doi: 10.1016/j.jfms.2010.01.001. Epub 2010 Mar 6.

Abstract

Point-of-care (POC) meters that determine whole blood triglyceride (TG) concentrations are used in human medicine to monitor both fasting and post-prandial TG concentrations. The aim of this study was to evaluate their performance for determining feline TG concentrations. A total of 116 venous blood samples were collected from 55 cats. TG concentrations were measured in whole blood using two meters: the Accutrend glucose cholesterol triglyceride (GCT) (GCT: Roche Diagnostics) and PTS CardioChek (PTS - Polymer Technology Systems), and results compared to those determined by a National Association of Testing Authorities (NATA) accredited veterinary laboratory. The GCT was not suitable for use in cats with normal TG concentrations (<0.9 mmol/l), as it overestimated almost 80% of the values; however, this device performed better with TG concentrations between 0.9 and 2.0 mmol/l. The PTS meter performed well in cats with normal TG concentrations, correctly classifying 90% of values as 'normal', and fairly well with TG concentrations <2.0 mmol/l. The PTS meter could be used to determine whether cats have normal fasting TG concentrations or predict mild elevations in serum TG, whereas the GCT meter can only be used to predict cats with elevated TG concentrations. Although both meters have limitations in determining some TG concentrations, the PTS in particular, could be used as a screening tool to distinguish normal cats to those with hypertriglyceridaemia.

摘要

用于测定全血甘油三酯(TG)浓度的即时检测(POC)血糖仪在人类医学中用于监测空腹和餐后TG浓度。本研究的目的是评估它们测定猫TG浓度的性能。从55只猫身上共采集了116份静脉血样本。使用两种血糖仪测定全血中的TG浓度:Accutrend葡萄糖胆固醇甘油三酯(GCT)血糖仪(GCT:罗氏诊断公司)和PTS CardioChek血糖仪(PTS - 聚合物技术系统公司),并将结果与由澳大利亚国家测试机构协会(NATA)认可的兽医实验室测定的结果进行比较。GCT血糖仪不适用于TG浓度正常(<0.9 mmol/l)的猫,因为它高估了近80%的值;然而,该设备在TG浓度为0.9至2.0 mmol/l之间时表现较好。PTS血糖仪在TG浓度正常的猫中表现良好,将90%的值正确分类为“正常”,在TG浓度<2.0 mmol/l时表现也较好。PTS血糖仪可用于确定猫的空腹TG浓度是否正常或预测血清TG的轻度升高,而GCT血糖仪只能用于预测TG浓度升高的猫。尽管两种血糖仪在测定某些TG浓度时都有局限性,但特别是PTS血糖仪可作为一种筛查工具,用于区分正常猫和高甘油三酯血症猫。

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