Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Cad Saude Publica. 2010 Jan;26(1):135-42. doi: 10.1590/s0102-311x2010000100014.
The study investigated the association between dietary patterns and oral cancer as part of a Latin American multicenter hospital-based case-control study, and included 210 incident cases of oral cancer and 251 controls. Dietary data were collected using a Food Frequency Questionnaire (FFQ). Factor analysis was used to define dietary patterns, which were categorized into terciles. Odds ratios (OR) with 95% confidence intervals (95%CI) were calculated using unconditional multiple logistic regression. The patterns 'prudent', characterized mainly by vegetables and fruits, and 'traditional', by rice, and pulses showed an inverse association with oral cancer for the higher tercile, respectively, OR = 0.44; 95%CI: 0.25-0.75, p value for trend (p tend) = 0.03; OR = 0.53; 95%CI: 0.30-0.93, p tend = 0.06. The 'snacks pattern' was not associated with oral cancer. Besides the protective effect of a diet rich in vegetables and fruit, our data suggest that the traditional Brazilian diet, consisting mostly of rice and beans, may improve protection against oral cancer.
本研究旨在探讨饮食模式与口腔癌之间的关联，这是拉丁美洲多中心医院病例对照研究的一部分，共纳入了 210 例口腔癌新发病例和 251 名对照。饮食数据通过食物频率问卷（FFQ）收集。采用因子分析定义饮食模式，并将其分为三分位数。采用非条件多因素逻辑回归计算比值比（OR）及其 95%置信区间（95%CI）。模式“谨慎”主要由蔬菜和水果组成，模式“传统”由米饭和豆类组成，与口腔癌的高三分位数呈负相关，OR 分别为 0.44（95%CI：0.25-0.75，趋势检验 p 值（p 趋势）= 0.03）和 OR 为 0.53（95%CI：0.30-0.93，p 趋势 = 0.06）。“零食模式”与口腔癌无关。除了富含蔬菜和水果的饮食具有保护作用外，我们的数据还表明，以米饭和豆类为主的传统巴西饮食可能会更好地预防口腔癌。
