Instituto Brasileiro de Oftalmologia e Prevenção da Cegueira, Salvador, BA.
Rev Soc Bras Med Trop. 2009 Nov-Dec;42(6):633-7. doi: 10.1590/s0037-86822009000600004.
In order to determine the prevalence of ocular lesions in HTLV-1 infected patients in Salvador Bahia, a transversal study was conducted on 140 HTLV-1 infected patients (90 asymptomatic and 50 tropical spastic paraparesis/HTLV-1-associated myelopathy) between June 2004 and November 2005. The ophthalmological examination included visual acuity measurement, ocular motility, biomicroscopy of the anterior and posterior chambers, intraocular pressure and evaluation of lachrymal secretion. Observation verified 4 (2.8%) out of 140 patients with uveitis (two patients had intermediate uveitis and two had pan-uveitis) and 39 (36.4%) out of 107 patients with keratoconjunctivitis sicca. The prevalence of Keratoconjunctivitis sicca was significantly higher among the TSP/HAM patients (OR age adjusted=3.64; 95%CI 1.59-8.32). Uveitis and corneal opacities were also important findings, indicating the strong need for periodic ophthalmological follow-up in all HTLV-1 subjects.
为了确定巴伊亚州萨尔瓦多 HTLV-1 感染患者眼部病变的流行情况，我们于 2004 年 6 月至 2005 年 11 月对 140 例 HTLV-1 感染患者（90 例无症状和 50 例热带痉挛性截瘫/HTLV-1 相关脊髓病）进行了横断面研究。眼科检查包括视力测量、眼球运动、眼前节和后节的生物显微镜检查、眼压和泪液分泌评估。观察发现，140 例患者中有 4 例（2.8%）患有葡萄膜炎（2 例为中间葡萄膜炎，2 例为全葡萄膜炎），107 例患者中有 39 例（36.4%）患有干燥性角结膜炎。干燥性角结膜炎在 TSP/HAM 患者中的患病率明显更高（调整年龄后的 OR=3.64；95%CI 1.59-8.32）。葡萄膜炎和角膜混浊也是重要的发现，表明所有 HTLV-1 患者都需要定期进行眼科随访。
