Oliveira Eveny Cristine Luna de, Pontes Elenir Rose Jardim Cury, Cunha Rivaldo Venâncio da, Fróes Iris Bucker, Nascimento Delso do
Curso de Mestrado em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS.
Rev Soc Bras Med Trop. 2009 Nov-Dec;42(6):682-5. doi: 10.1590/s0037-86822009000600014.
Dengue is a neglected disease with high morbidity and mortality among children and adults that occurs mainly in tropical and subtropical regions. The objective of this study was to evaluate hematological changes in patients with clinical manifestations of dengue. Medical records relating to 543 cases of dengue virus 3 that occurred during the 2007 epidemic in Campo Grande, Mato Grosso do Sul, were studied. Cases of classic dengue predominated (90.2%), with mild clinical manifestations lacking complications. The main hematological findings were leukopenia (68.3%), thrombocytopenia (66.5%), lymphocytopenia (67.2%) and atypical lymphocytes (67%). In dengue hemorrhagic fever, thrombocytopenia was more prolonged and the number of atypical lymphocytes was higher, while the other hematological abnormalities presented daily evolution similar to those in classic dengue. The hematological changes observed in dengue present according to the clinical course of the disease and its severity.
登革热是一种被忽视的疾病，在儿童和成人中发病率和死亡率都很高，主要发生在热带和亚热带地区。本研究的目的是评估有登革热临床表现患者的血液学变化。对2007年在南马托格罗索州大坎普发生的543例登革热病毒3感染病例的医疗记录进行了研究。典型登革热病例占主导（90.2%），临床表现轻微，无并发症。主要血液学发现为白细胞减少（68.3%）、血小板减少（66.5%）、淋巴细胞减少（67.2%）和异型淋巴细胞（67%）。在登革出血热中，血小板减少持续时间更长，异型淋巴细胞数量更多，而其他血液学异常的每日变化情况与典型登革热相似。登革热中观察到的血液学变化根据疾病的临床病程及其严重程度而呈现不同表现。
