激光散斑对比成像在生物医学光学中的应用。
Laser speckle contrast imaging in biomedical optics.
机构信息
Harvard Medical School, Massachusetts General Hospital, Anthinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA.
出版信息
J Biomed Opt. 2010 Jan-Feb;15(1):011109. doi: 10.1117/1.3285504.
Abstract
First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field imaging of blood flow. Recently laser speckle contrast imaging has gained increased attention, in part due to its rapid adoption for blood flow studies in the brain. We review the underlying physics of speckle contrast imaging and discuss recent developments to improve the quantitative accuracy of blood flow measures. We also review applications of laser speckle contrast imaging in neuroscience, dermatology and ophthalmology.
摘要
激光散斑对比成像于 20 世纪 80 年代首次问世，是一种用于血流全场成像的强大工具。最近，激光散斑对比成像受到了越来越多的关注，部分原因是它在大脑血流研究中得到了迅速采用。我们回顾了散斑对比成像的基础物理学，并讨论了提高血流测量定量准确性的最新进展。我们还回顾了激光散斑对比成像在神经科学、皮肤病学和眼科学中的应用。
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