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用频域光声光谱法测量 Intralipid 的温度相关光学特性。

Temperature-dependent optical properties of Intralipid measured with frequency-domain photon-migration spectroscopy.

机构信息

The University of Waikato, Hamilton, New Zealand.

出版信息

J Biomed Opt. 2010 Jan-Feb;15(1):017003. doi: 10.1117/1.3290820.

DOI:10.1117/1.3290820
PMID:20210477
Abstract

We present the temperature dependence of absorption and reduced scattering coefficients of 1.8% Intralipid measured by frequency-domain photon-migration spectroscopy between 710 and 850 nm. These measurements were made in the physiologically relevant 30 to 40 degrees C temperature range. The temperature coefficients for absorption were consistent during heating and cooling and follow closely other reported results. The change in absorption coefficient at 740 nm suggests that a minimum temperature change of 4 degrees C is observable within the error limits. We found that the reduced scattering coefficient shows a hysteresis with temperature at 740 nm. The temperature coefficient for reduced scattering determined from heating cycle measurements agrees with theory and other measurements within the error limits.

摘要

我们展示了在 710nm 至 850nm 之间通过频域光迁移光谱法测量的 1.8%Intralipid 的吸收和散射系数随温度的变化。这些测量是在生理相关的 30 至 40°C 温度范围内进行的。在加热和冷却过程中,吸收系数的温度系数保持一致,并且与其他已报道的结果非常接近。在 740nm 处吸收系数的变化表明,在误差范围内可以观察到最小 4°C 的温度变化。我们发现,在 740nm 处,散射系数随温度呈现滞后现象。从加热循环测量中确定的散射系数温度系数在误差范围内与理论和其他测量结果一致。

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