Aghayev Emin, Jackowski Christian, Christe Andreas, Thali Michael
Institute of Forensic Medicine, University of Bern, Buehlstrasse 20, CH-3012 Bern, Switzerland.
J Forensic Leg Med. 2010 Apr;17(3):164-8. doi: 10.1016/j.jflm.2009.10.001. Epub 2009 Nov 28.
In clinical medicine, plane radiography is used for detecting the remains of medications in the stomach in oral medication intoxication cases. Since postmortem computed tomography (CT), performed prior to autopsy, is currently intensively entering the forensic routine, the technique was applied to three fatal cases of oral medication intoxication. Here we report CT and autopsy findings for these cases. In all three cases, hyperdense areas within the stomach content were documented. The measurement of Hounsfield Units (HU) beyond 74HU showed mean values of 338, 88 and 98HU. Postmortem CT also showed brain edema and pulmonary aspiration in one case. At autopsy, tablet remains in the stomach were detected microscopically in all three cases. The ex vivo CT scans of the ingested medicaments showed similar HU values. Despite the fact that further case studies are necessary beyond this one, and in spite of its limitations, postmortem CT was found to be a useful screening and documentation method for stomach contents in oral medication intoxication.
在临床医学中，平面放射摄影用于检测口服药物中毒病例中胃内的药物残留。由于尸检前进行的死后计算机断层扫描（CT）目前正广泛应用于法医常规检查，该技术被应用于三例口服药物中毒致死病例。在此，我们报告这些病例的CT和尸检结果。在所有三例病例中，均记录到胃内容物内的高密度区域。亨氏单位（HU）测量值超过74HU，其平均值分别为338、88和98HU。死后CT还显示其中一例病例存在脑水肿和肺吸入。尸检时，在所有三例病例中均通过显微镜检测到胃内有片剂残留。摄入药物的离体CT扫描显示出相似的HU值。尽管在此之外还需要进一步的病例研究，并且尽管存在局限性，但死后CT被发现是一种用于口服药物中毒胃内容物的有用筛查和记录方法。
