McKusick-Nathans Institute of Genetic Medicine, High Throughput Biology Center, Johns Hopkins University School of Medicine, 733 North Broadway, Baltimore, MD 21205, USA.
Nucleic Acids Res. 2010 May;38(8):2603-6. doi: 10.1093/nar/gkq143. Epub 2010 Mar 8.
GeneDesign is a set of web applications that provides public access to a nucleotide manipulation pipeline for synthetic biology. The server is public and freely accessible, and the source is available for download under the New BSD License. Since GeneDesign was published and made publicly available 3 years ago, we have made its code base more efficient, added several algorithms and modules, updated the restriction enzyme library, added batch processing capabilities, and added several command line modules, all of which we briefly describe here.
GeneDesign 是一组网络应用程序,为合成生物学提供了公共访问核苷酸操作管道。服务器是公开的,可自由访问,源代码可根据新 BSD 许可证下载。自从三年前 GeneDesign 发布并公开以来,我们已经使其代码库更加高效,增加了几个算法和模块,更新了限制酶库,增加了批处理功能,并增加了几个命令行模块,我们在这里简要介绍一下。