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青少年2型糖尿病的治疗:关于随机对照研究的争论

Treatment of type 2 diabetes in youth: An argument for randomized controlled studies.

作者信息

Dean H

机构信息

Department of Pediatrics, University of Manitoba, Winnipeg, Manitoba.

出版信息

Paediatr Child Health. 1999 May;4(4):265-9. doi: 10.1093/pch/4.4.265.

DOI:10.1093/pch/4.4.265
PMID:20212932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2827719/
Abstract

In North America, type 2 diabetes occurs in youth (children and adolescents) of specific ethnic backgrounds, including youth of Aboriginal, Hispanic, Asian, Pacific Islander, Japanese and African-American descent. The treatment of youth with type 2 diabetes represents a unique challenge for paediatricians because of physicians' long experience with this disease in adults but its short history in youth. The education and management of type 2 diabetes in youth must recognize the unique developmental, emotional and social issues associated with this age group, as well as the cultural, linguistic, geographic and socioeconomic issues associated with these populations. With the exception of insulin, the drugs used for adults with type 2 diabetes have not been studied in youth. There is an urgent need for long term, multicentre randomized controlled studies of oral drugs for type 2 diabetes in youth.

摘要

在北美,2型糖尿病发生在特定种族背景的青少年(儿童和青少年)中,包括原住民、西班牙裔、亚裔、太平洋岛民、日本裔和非裔美国青少年。由于医生在成人中治疗这种疾病经验丰富,但在青少年中治疗2型糖尿病的历史较短,因此对儿科医生来说,治疗青少年2型糖尿病是一项独特的挑战。青少年2型糖尿病的教育和管理必须认识到与这个年龄组相关的独特发育、情感和社会问题,以及与这些人群相关的文化、语言、地理和社会经济问题。除胰岛素外,用于成人2型糖尿病的药物尚未在青少年中进行研究。迫切需要对青少年2型糖尿病口服药物进行长期、多中心随机对照研究。

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本文引用的文献

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