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原住民儿童2型糖尿病:评估与预防疾病的合作举措。

Type 2 diabetes in First Nation children: A collaborative effort to assess and prevent disease.

作者信息

Smith W, Gowanlock W, Babcock K

机构信息

Paediatric Diabetic Education Centre, Orillia Soldiers Memorial Hospital, Orillia, Ontario.

出版信息

Paediatr Child Health. 2001 Dec;6(10):755-9. doi: 10.1093/pch/6.10.755.

DOI:10.1093/pch/6.10.755
PMID:20084151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2805988/
Abstract

Type 2 diabetes occurs in special groups of children. One of the highest rates of type 2 diabetes in the world occurs in First Nation people. Screening of First Nation children has been recommended. To diagnose diabetes earlier and prevent complications in adulthood, a program of screening and primary prevention of First Nation people must begin with children. One hundred fifteen school-aged First Nation children were approached to participate in the present study, and 93% of the children completed the study. Eight (7%) of the study participants had abnormal capillary blood glucose levels, but no cases of type 2 diabetes were confirmed. Risk factors related to exercise, diet, blood pressure and body mass index were identified. The present paper describes a collaborative program with a small Paediatric Diabetic Education Center and the Beausoleil First Nation people.

摘要

2型糖尿病发生在特殊的儿童群体中。世界上2型糖尿病发病率最高的群体之一是原住民。有人建议对原住民儿童进行筛查。为了更早诊断糖尿病并预防成年期并发症,针对原住民的筛查和一级预防项目必须从儿童开始。本研究邀请了115名学龄原住民儿童参与,93%的儿童完成了研究。8名(7%)研究参与者的毛细血管血糖水平异常,但未确诊2型糖尿病病例。确定了与运动、饮食、血压和体重指数相关的风险因素。本文描述了一个与小型儿科糖尿病教育中心和博索莱尔原住民合作的项目。

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本文引用的文献

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Treatment of type 2 diabetes in youth: An argument for randomized controlled studies.青少年2型糖尿病的治疗:关于随机对照研究的争论
Paediatr Child Health. 1999 May;4(4):265-9. doi: 10.1093/pch/4.4.265.
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Is a low leptin concentration, a low resting metabolic rate, or both the expression of the "thrifty genotype"? Results from Mexican Pima Indians.低瘦素浓度、低静息代谢率,还是两者皆是“节俭基因型”的表现?来自墨西哥皮马印第安人的研究结果。
Am J Clin Nutr. 1998 Nov;68(5):1053-7. doi: 10.1093/ajcn/68.5.1053.
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An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians.对皮马印第安人中与II型糖尿病和体重指数相关的基因座进行常染色体基因组扫描。
Am J Hum Genet. 1998 Oct;63(4):1130-8. doi: 10.1086/302061.
10
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.磺脲类或胰岛素强化血糖控制与传统治疗及2型糖尿病患者并发症风险的比较(英国前瞻性糖尿病研究[UKPDS 33])。英国前瞻性糖尿病研究(UKPDS)小组
Lancet. 1998 Sep 12;352(9131):837-53.