无症状性传播感染男性的精液血浆HIV水平。
Seminal plasma HIV levels in men with asymptomatic sexually transmitted infections.
作者信息
Rieg G, Butler D M, Smith D M, Daar E S
机构信息
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center and the David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
出版信息
Int J STD AIDS. 2010 Mar;21(3):207-8. doi: 10.1258/ijsa.2009.009331.
Abstract
The effect of asymptomatic sexually transmitted urethral infections on human immunodeficiency virus (HIV) RNA viral load in semen is poorly defined. We studied five such patients. Those on antiretrovirals (n = 2) had lower seminal plasma viral loads (SPVL) (2.11 and 1.98 log(10) copies/mL) than those not on antiretrovirals (n = 3) (2.27-3.78 log(10) copies/mL). One patient who was not taking antiretrovirals had a 94% decline in SPVL after treatment of asymptomatic Chlamydia trachomatis urethritis, suggesting that asymptomatic infection may be a co-factor for HIV transmission.
摘要
无症状性传播尿道感染对精液中人类免疫缺陷病毒（HIV）RNA病毒载量的影响尚不明确。我们研究了5例此类患者。接受抗逆转录病毒治疗的患者（n = 2）精液血浆病毒载量（SPVL）（2.11和1.98 log₁₀拷贝/毫升）低于未接受抗逆转录病毒治疗的患者（n = 3）（2.27 - 3.78 log₁₀拷贝/毫升）。1例未接受抗逆转录病毒治疗的患者在无症状沙眼衣原体尿道炎治疗后SPVL下降了94%，这表明无症状感染可能是HIV传播的一个协同因素。
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