Department of Medical Genetics, Athens University Medical School, Choremio Research Laboratory, Aghia Sofia Children's Hospital, Goudi, Athens, Greece.
Fetal Diagn Ther. 2010;27(3):149-55. doi: 10.1159/000295210. Epub 2010 Mar 9.
To assess knowledge and attitudes towards prenatal diagnostic procedures among pregnant women living in Greece who underwent amniocentesis or chorionic villus sampling in relation to underlying demographic, lifestyle and medical history predictors.
354 women, upon receiving the results, were interviewed in person. A structured questionnaire was answered based upon sociodemographic, educational, lifestyle and medical history variables, as well as questions pertaining to the women's knowledge, use and opinion of prenatal tests. Summary statistics and multiple logistic regression analyses were performed.
No prior information on prenatal diagnostic procedures was reported in 29% or on prenatal screening tests in 50% of the study subjects. Women with no history of inherited diseases were about threefold more likely to have inadequate knowledge (OR = 2.72, p = 0.01) as were women of non-Greek nationality (OR = 3.27, p = 0.02) as well as those who reported being unaware of the health consequences of smoking during pregnancy (OR = 2.50, p = 0.005). By contrast, women of higher education were over twofold more likely to attain a higher level of knowledge of prenatal diagnostic procedures (OR = 0.51, p = 10(-4)) as were those reported reading the popular press (OR = 0.44, p = 10(-4)).
In spite of the increased availability of prenatal diagnosis, much more is needed to be done in order to improve the efficiency of prenatal counseling, especially in immigrants and women with a low educational background.
评估在希腊进行羊膜穿刺术或绒毛膜取样的孕妇对产前诊断程序的知识和态度，分析其与潜在的人口统计学、生活方式和病史预测因素的关系。
在获得结果后，对 354 名妇女进行了面对面访谈。根据社会人口统计学、教育、生活方式和病史变量以及与妇女对产前检查的知识、使用和意见相关的问题，回答了一份结构化问卷。进行了描述性统计和多因素逻辑回归分析。
29%的研究对象之前没有接受过关于产前诊断程序的信息，50%的研究对象之前没有接受过产前筛查测试。没有遗传病史的妇女对产前诊断程序的了解不足的可能性是三倍（OR=2.72，p=0.01），非希腊籍妇女（OR=3.27，p=0.02）和那些表示不知道吸烟对怀孕健康后果的妇女（OR=2.50，p=0.005）也是如此。相比之下，受教育程度较高的妇女对产前诊断程序的了解程度更高的可能性是两倍多（OR=0.51，p=10(-4)），而那些表示阅读大众媒体的妇女（OR=0.44，p=10(-4)）也是如此。
尽管产前诊断的可及性增加了，但仍需要做更多的工作来提高产前咨询的效率，特别是在移民和教育程度较低的妇女中。
