血清 C 反应蛋白和降钙素原浓度在指导肺炎链球菌性肺炎和军团菌性肺炎鉴别诊断和临床管理中的临床潜力。
Clinical potential of C-reactive protein and procalcitonin serum concentrations to guide differential diagnosis and clinical management of pneumococcal and Legionella pneumonia.
机构信息
Medical University of Innsbruck, Department of Internal Medicine I, Clinical Immunology and Infectious Diseases, Anichstrasse 35, A-6020 Innsbruck, Austria.
出版信息
J Clin Microbiol. 2010 May;48(5):1915-7. doi: 10.1128/JCM.01348-09. Epub 2010 Mar 10.
Abstract
We retrospectively analyzed the records of 61 hospitalized patients with community-acquired pneumonia (CAP) caused by Streptococcus pneumoniae or Legionella pneumophila. We found that serum procalcitonin and sodium concentrations were significantly lower, and ferritin levels were significantly higher, in patients infected with L. pneumophila than in those infected with S. pneumoniae. The ratio of C-reactive protein to procalcitonin significantly distinguished between the groups. High procalcitonin levels were associated with an adverse clinical course.
摘要
我们回顾性分析了 61 例由肺炎链球菌或嗜肺军团菌引起的社区获得性肺炎（CAP）住院患者的记录。我们发现，感染嗜肺军团菌的患者血清降钙素原和钠浓度显著降低，而铁蛋白水平显著升高，与感染肺炎链球菌的患者相比。C 反应蛋白与降钙素原的比值能显著区分两组。高水平的降钙素原与不良临床病程有关。
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