多中心比较 ISO 标准 20776-1 和连续 2 倍稀释程序，以稀释亲水和疏水性抗真菌药物进行药敏试验。
Multicenter comparison of the ISO standard 20776-1 and the serial 2-fold dilution procedures to dilute hydrophilic and hydrophobic antifungal agents for susceptibility testing.
机构信息
Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo Km. 2, 28220 Majadahonda, Madrid, Spain.
出版信息
J Clin Microbiol. 2010 May;48(5):1918-20. doi: 10.1128/JCM.00123-10. Epub 2010 Mar 10.
Abstract
A multicenter study was conducted to assess the accuracy of the ISO standard 20776-1 and the serial 2-fold dilution procedures for antifungal susceptibility testing. Fluconazole trays can be accurately prepared by following ISO and serial dilution schemes. However, itraconazole trays showed a significant lack of reproducibility that was independent of which method was followed.
摘要
一项多中心研究评估了 ISO 标准 20776-1 和连续 2 倍稀释程序用于抗真菌药敏试验的准确性。通过遵循 ISO 和连续稀释方案，可以准确地制备氟康唑药敏试验板。然而，伊曲康唑药敏试验板表现出明显的不可重复性，与所遵循的方法无关。
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