Colombo A L, Barchiesi F, McGough D A, Fothergill A W, Rinaldi M G
Department of Pathology, University of Texas-Health Science Center at San Antonio, USA.
J Antimicrob Chemother. 1995 Jul;36(1):93-100. doi: 10.1093/jac/36.1.93.
The E test strip (AB Biodisk, Solna, Sweden) as an antimicrobial susceptibility testing method is a new and promising tool with broad application in microbiology. This method is less labour intensive than broth dilution methods and may be useful for testing individual clinical isolates. In contrast to several publications comparing E test antibacterial strips with NCCLS reference methods, there is little information about the performance of E test antifungal strips. This study compared fluconazole and itraconazole MICs obtained by E test with a microbroth dilution method performed to NCCLS guidelines. Fluconazole and itraconazole E test results exhibited good correlation with the broth microdilution (82% and 81% agreement within +/- 1 two-fold dilution, respectively). The E test is easy to perform and generates MICs for Candida species in 24 h.
E试验条（AB生物盘公司，瑞典索尔纳）作为一种抗菌药物敏感性检测方法，是一种新型且有前景的工具，在微生物学领域有广泛应用。该方法比肉汤稀释法所需人力更少，可能有助于检测单个临床分离株。与多篇比较E试验抗菌条与NCCLS参考方法的文献不同，关于E试验抗真菌条性能的信息很少。本研究将通过E试验获得的氟康唑和伊曲康唑的最低抑菌浓度（MIC）与按照NCCLS指南进行的微量肉汤稀释法所测结果进行了比较。氟康唑和伊曲康唑的E试验结果与肉汤微量稀释法显示出良好的相关性（在±1个两倍稀释范围内的一致性分别为82%和81%）。E试验操作简便，24小时内即可得出念珠菌属的MIC。
