Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
Retina. 2010 Apr;30(4 Suppl):S63-5. doi: 10.1097/IAE.0b013e3181cbda0f.
The purpose of this study was to report a case of a 7-year-old girl with unilateral, multifocal Reese Ellsworth Stage Vb retinoblastoma who was successfully treated using intraarterial chemotherapy infusion as the primary therapy.
This is an interventional case report. A 7-year-old girl presented with advanced unilateral retinoblastoma. The patient received intraarterial melphalan infusion therapy as the primary treatment.
Complete tumor resolution was seen at 1 month after intraarterial melphalan infusion.
This case of advanced retinoblastoma in a 7-year-old girl was successfully treated with intraarterial melphalan infusion alone. Treatment resulted in complete resolution of the tumor 1 month after treatment. In comparison with systemic chemotherapy, intraarterial melphalan infusion therapy may be a less toxic and more effective primary treatment option in the future management of advanced retinoblastoma.
本研究旨在报告一例 7 岁单侧、多灶 Reese-Ellsworth 第 Vb 期视网膜母细胞瘤患儿，该患儿成功接受了以动脉内化疗灌注作为主要治疗方法。
这是一个介入性病例报告。一名 7 岁女孩因晚期单侧视网膜母细胞瘤就诊。该患者接受了动脉内注射美法仑灌注治疗作为主要治疗。
动脉内注射美法仑灌注治疗后 1 个月，肿瘤完全消退。
本例 7 岁晚期视网膜母细胞瘤患儿成功单独接受动脉内美法仑灌注治疗。治疗后 1 个月肿瘤完全消退。与全身化疗相比，动脉内美法仑灌注治疗可能是未来治疗晚期视网膜母细胞瘤更有效、毒性更小的主要治疗选择。
