Suppr超能文献

快速演变的巨大皮肤纤维瘤

Rapidly evolving giant dermatofibroma.

作者信息

Lang K J, Lidder S, Hofer M, Graham C, Taylor A

机构信息

Department of General Surgery, Stoke Mandeville Hospital, Mandeville Road, Aylesbury, Bucks, HP21 8AL, UK.

出版信息

Case Rep Med. 2010;2010:620910. doi: 10.1155/2010/620910. Epub 2010 Mar 9.

Abstract

Dermatofibroma, also known as "fibrous histiocytoma", is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis. Although it is commonly present as a brownish nodule the legs of females, it may also arise on the upper extremities, trunk, and rarely on the head. The exact pathogenesis is unclear. However, it is widely believed that the originating insult to the dermis is a folliculitis, an arthropod bite, or an unspecified initial inflammatory condition. Giant dermatofibromas of greater than 5 cm in diameter are rare, with only 22 cases reported in the literature. We present a case of a rapidly evolving pedunculated mass in the groin of a male patient. Histological examination confirmed this to be a giant dermatofibroma. Though this specimen cannot is not confirmed as such, the cellular subtype is sometimes present as a larger lesion with anecdotal reports of local recurrence and distant metastases. The clinical and radiological features which were somewhat suspicious of malignancy are considered in the context of the definitive pathological diagnosis of a benign lesion.

摘要

皮肤纤维瘤,也称为“纤维组织细胞瘤”,是一种良性的真皮或皮下肿物,其特征为真皮内梭形成纤维细胞和巨噬细胞的增殖,边界不清。虽然它通常表现为女性腿部的褐色结节,但也可能出现在上肢、躯干,很少出现在头部。确切的发病机制尚不清楚。然而,人们普遍认为,对真皮的初始损伤是毛囊炎、节肢动物叮咬或未明确的初始炎症状态。直径大于5厘米的巨大皮肤纤维瘤很少见,文献中仅报道了22例。我们报告一例男性患者腹股沟区迅速增大的带蒂肿物。组织学检查证实为巨大皮肤纤维瘤。虽然该标本未被确认为此,但细胞亚型有时表现为较大的病变,并有局部复发和远处转移的零星报道。在良性病变的明确病理诊断背景下,考虑了一些怀疑恶性的临床和放射学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1d5/2836174/042cd0060ff9/CRM2010-620910.001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验