Department of Community Health & Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Best Pract Res Clin Rheumatol. 2010 Apr;24(2):167-79. doi: 10.1016/j.berh.2009.12.005.
Understanding prognosis is important in managing low back pain. In this article, we discuss the available evidence on low back pain prognosis and describe how prognostic evidence can be used to inform clinical decision making. We describe three main types of related prognosis questions: 'What is the most likely course?' (Course studies); 'What factors are associated with, or determine, outcome?' (Prognostic factor or explanatory studies); and 'Can we identify risk groups who are likely to have different outcomes?' (Risk group or outcome prediction studies). Most low back pain episodes are mild and rarely disabling, with only a small proportion of individuals seeking care. Among those presenting for care, there is variability in outcome according to patient characteristics. Most new episodes recover within a few weeks. However, recurrences are common and individuals with chronic, long-standing low back pain tend to show a more persistent course. Studies of mixed primary care populations indicate 60-80% of health-care consulters will continue to have pain after a year. Important low back pain prognostic factors are related to the back pain episode, the individual and psychological characteristics, as well as the work and social environment. Although numerous studies have developed prediction models in the field, most models/tools explain less than 50% of outcome variability and few have been tested in independent samples. We discuss limitations and future directions for research in the area of low back pain prognosis.
了解预后对于管理下腰痛非常重要。在本文中,我们讨论了下腰痛预后的现有证据,并描述了如何利用预后证据为临床决策提供信息。我们描述了三种主要的预后问题类型:“最有可能的病程是什么?”(病程研究);“哪些因素与结局相关或决定结局?”(预后因素或解释性研究);“我们能否识别出可能有不同结局的风险群体?”(风险群体或结局预测研究)。大多数下腰痛发作是轻度的,很少导致残疾,只有一小部分人需要治疗。在那些寻求治疗的人中,根据患者的特征,结局存在差异。大多数新发发作在数周内恢复。然而,复发很常见,患有慢性、长期下腰痛的个体往往表现出更持续的病程。混合初级保健人群的研究表明,60-80%的健康咨询者在一年后仍会有疼痛。重要的下腰痛预后因素与腰痛发作、个体和心理特征以及工作和社会环境有关。尽管该领域已经有许多研究开发了预测模型,但大多数模型/工具仅解释了不到 50%的结局变异性,并且很少在独立样本中进行过测试。我们讨论了下腰痛预后研究领域的局限性和未来方向。