Surat Municipal Institute of Medical, Education & Research, Umarwada, Surat-395 009, Gujarat, India.
Indian J Dermatol Venereol Leprol. 2010 Mar-Apr;76(2):215. doi: 10.4103/0378-6323.60542.
Kaposi's sarcoma (KS) is a multifocal cutaneous and extra cutaneous vascular proliferative disorder. In India, there are only a few cases of HIV-associated KS in published literature. A 26-year-old married man presented with asymptomatic elevated skin lesions over the face, trunk, both upper limbs and lower limbs with a duration of one-and-a-half months. Cutaneous examination revealed multiple violaceous papules and nodules, on the face (right upper and lower eyelids, upper lip), trunk and proximal part of both limbs. Oral cavity showed erythematous plaques, two in number, on the hard palate. Skin biopsy showed proliferation of thin walled capillaries with formation of slit like spaces, spindle cell proliferation, abundant extravasation of RBCs and moderately dense inflammatory infiltrate in the dermis. Thus a clinical diagnosis of cutaneous KS was confirmed. On testing with ELISA for HIV, the patient was for the first time diagnosed as HIV reactive. Thus KS was the presenting manifestation of HIV disease.
卡波西肉瘤（KS）是一种多灶性皮肤和皮肤外血管增生性疾病。在印度，发表的文献中仅有少数几例与 HIV 相关的 KS 病例。一名 26 岁已婚男性出现无症状性高出皮肤的病变，累及面部、躯干、双上肢和双下肢，病程为一个半月。皮肤检查显示面部（右上、下眼睑、上唇）、躯干和四肢近端有多个紫红色丘疹和结节。口腔有 2 个红斑斑块，位于硬腭。皮肤活检显示薄壁毛细血管增生，形成缝隙样空间，梭形细胞增生，真皮内红细胞外溢丰富，中度密集炎症浸润。因此，临床诊断为皮肤 KS。通过 ELISA 检测 HIV，患者首次被诊断为 HIV 反应性。因此，KS 是 HIV 疾病的首发表现。
