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心力衰竭患者的睡眠呼吸暂停。

Sleep apnea in heart failure patients.

机构信息

Division of Cardiology, Pneumology and Angiology, Department of Medicine, University Hospital Düsseldorf, Düsseldorf, Germany.

出版信息

Panminerva Med. 2010 Mar;52(1):79-89.

Abstract

Growing evidence suggests that there may be a strong pathophysiologic link between congestive heart failure (CHF) and nocturnal breathing disorders due to nocturnal oxygen desaturation, intrathoracic pressure swings and sympathetic activation. It seems that sleep apnea contributes to systolic and diastolic heart failure, reduced left and right ventricular function and arrhythmia (e.g. atrial fibrillation). Therefore treatment of sleep apnea might alleviate cardiac symptoms and improve cardiac function. Nevertheless, the exact role of long term treatment of sleep apnea in heart failure patients remains to be elucidated.

摘要

越来越多的证据表明,充血性心力衰竭(CHF)和夜间呼吸障碍之间可能存在强烈的病理生理联系,原因是夜间氧饱和度下降、胸腔内压力波动和交感神经激活。睡眠呼吸暂停似乎会导致收缩性和舒张性心力衰竭、左心室和右心室功能降低以及心律失常(如心房颤动)。因此,治疗睡眠呼吸暂停可能会缓解心脏症状并改善心脏功能。然而,睡眠呼吸暂停的长期治疗在心力衰竭患者中的确切作用仍有待阐明。

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