Berrow Emma J, Bartlett Hannah E, Eperjesi Frank, Gibson Jonathan M
Ophthalmic Research Group, School of Life and Health Sciences, Aston University, Birmingham B4 7ET, United Kingdom.
Doc Ophthalmol. 2010 Aug;121(1):51-62. doi: 10.1007/s10633-010-9226-1. Epub 2010 Mar 16.
With an ageing population, the number of age-related macular disease (ARMD) cases will inevitably rise. This gives greater impetus for the need to identify the disease earlier and assess treatments to slow disease progression. Differing electroretinogram (ERG) modalities have been reviewed in relation to the objective assessment of retinal function in ARMD and for monitoring the effectiveness of clinical interventions. Conflicting results have been found with regard to the efficacy of ERG findings in the investigation of ARMD in previous years. The newer multifocal ERG paradigm provides spatial topographical information about retinal function in ARMD. It has shown promising results in monitoring effectiveness of clinical interventions and studies are continuing in this area. Better knowledge of retinal function in ARMD may lead to enhanced treatments at each phase of the disease.
随着人口老龄化，年龄相关性黄斑疾病（ARMD）的病例数量将不可避免地增加。这为更早地识别该疾病并评估减缓疾病进展的治疗方法提供了更大的动力。关于ARMD视网膜功能的客观评估以及监测临床干预效果，已经对不同的视网膜电图（ERG）模式进行了综述。在过去几年中，关于ERG检查结果在ARMD研究中的有效性存在相互矛盾的结果。更新的多焦ERG模式提供了关于ARMD视网膜功能的空间地形图信息。它在监测临床干预效果方面已显示出有希望的结果，并且该领域的研究仍在继续。对ARMD视网膜功能的更好了解可能会在疾病的每个阶段带来更好的治疗方法。
