Crit Care. 2010;14(1):118. doi: 10.1186/cc8841. Epub 2010 Feb 15.
Crystalloid and colloid solutions are used for resuscitation of the critically ill. One set of options, widely used today, are different preparations of hydroxyethyl starch (HES). However, the safety of HES regarding impairment of blood coagulation remains incompletely elucidated, a circumstance that limits its clinical use. Understanding mechanisms and potential differences between low-molecular and low-substituted HES and other HES solutions seems clinically relevant.
晶体液和胶体液被用于重症患者的复苏。目前广泛使用的一组选择是羟乙基淀粉(HES)的不同制剂。然而,HES 对凝血功能损害的安全性仍不完全清楚,这种情况限制了其临床应用。了解低分子和低取代 HES 与其他 HES 溶液之间的机制和潜在差异在临床上似乎是相关的。