Department of Physical Medicine and Rehabilitation, Ataturk Training and Research Hospital, Izmir, Türkiye.
Rheumatol Int. 2011 Jul;31(7):889-94. doi: 10.1007/s00296-010-1406-5. Epub 2010 Mar 18.
Ankylosing spondylitis (AS) is a chronic inflammatory disorder of the axial skeleton. In recent years, several authors reported an increased prevalence of sexual dysfunction among AS patients. We aimed to find out, whether the prevalence of erectile dysfunction among AS patients is different from age-matched healthy controls. Thirty-seven male patients with AS who were diagnosed according to the modified New York criteria and 67 normal healthy controls (NHC) were included in this study. Clinical characteristics of patients including age, disease duration and morning stiffness were noted. Disease activity was evaluated by using Bath AS disease activity index (BASDAI), functional statement was evaluated by using Bath AS functional index, and scores of spinal measurements were done by using Bath AS metrology index. Erectile function is evaluated using the International Index of Erectile Function (IIEF) scoring system. Health-related quality of life was assessed by short form 36. The mean age of the patients and controls were 42.8 + 10.8 and 43.6 + 5.9 years (P = 0.666). The prevalence of erectile dysfunction in AS patients and NHC were 35.1 and 26.9%, respectively (P = 0.335). There was no statistically significant difference between IIEF domain scores of AS patients and NHC except for the sexual desire domain (P = 0.014). Duration of morning stiffness and BASDAI was negatively correlated with sexual desire and overall satisfaction; however, they have no negative impact on erectile function, orgasmic function and intercourse satisfaction domains of IIEF. In this report, we showed that only the sexual desire domain of IIEF was significantly lower in AS patients. The prevalence of erectile dysfunction among AS patients is similar to NHC, which is a finding contrary to previous reports. AS patients do not suffer from erectile dysfunction, they rather have problems of satisfaction from the intercourse.
强直性脊柱炎(AS)是一种慢性炎症性疾病轴向骨骼。近年来,几位作者报道了 AS 患者性功能障碍的患病率增加。我们旨在了解 AS 患者勃起功能障碍的患病率是否与年龄匹配的健康对照组不同。本研究纳入了 37 名根据改良纽约标准诊断为 AS 的男性患者和 67 名正常健康对照者(NHC)。记录患者的临床特征,包括年龄、疾病持续时间和晨僵。使用 Bath AS 疾病活动指数(BASDAI)评估疾病活动,使用 Bath AS 功能指数评估功能状态,使用 Bath AS 计量指数评估脊柱评分。使用国际勃起功能指数(IIEF)评分系统评估勃起功能。使用简明健康状况调查问卷(SF-36)评估健康相关生活质量。患者和对照组的平均年龄分别为 42.8±10.8 岁和 43.6±5.9 岁(P=0.666)。AS 患者和 NHC 的勃起功能障碍患病率分别为 35.1%和 26.9%(P=0.335)。除性欲领域外(P=0.014),AS 患者与 NHC 的 IIEF 各领域评分均无统计学差异。晨僵时间和 BASDAI 与性欲和总体满意度呈负相关;然而,它们对 IIEF 的勃起功能、性高潮功能和性交满意度领域没有负面影响。在本报告中,我们表明只有 IIEF 的性欲领域在 AS 患者中显著降低。AS 患者勃起功能障碍的患病率与 NHC 相似,这与之前的报告结果相反。AS 患者没有勃起功能障碍,而是存在性交满意度的问题。