肺门淋巴结纤维化与实质性矽肺发展之间的关系。
The relation between fibrosis of hilar lymph glands and the development of parenchymal silicosis.
作者信息
Murray J, Webster I, Reid G, Kielkowski D
机构信息
National Centre for Occupational Health, Braamfontein, Republic of South Africa.
出版信息
Br J Ind Med. 1991 Apr;48(4):267-9. doi: 10.1136/oem.48.4.267.
The necropsy findings on the cardiorespiratory organs of 849 South African gold miners were analysed to test the hypothesis that fibrosis of the hilar lymph glands predisposes to the development of parenchymal silicotic nodules. Four hundred and eighty three cases had fibrosed glands, 34% of which also had parenchymal silicosis. By comparison, of 238 cases with silicosis, 88% had fibrosed glands. The proportion of cases with both silicosis and fibrosed glands, as well as those with gland fibrosis only, increased with increasing duration of exposure. As far as can be ascertained from a necropsy series such as this, it is possible that fibrosis of the lymph glands may predispose to the development of lung parenchymal silicosis.
对849名南非金矿工人的心肺器官尸检结果进行了分析，以检验肺门淋巴结纤维化易导致实质性矽肺结节形成这一假设。483例有淋巴结纤维化，其中34%也有实质性矽肺。相比之下，在238例矽肺病例中，88%有淋巴结纤维化。同时患有矽肺和淋巴结纤维化的病例比例，以及仅患有淋巴结纤维化的病例比例，均随接触时间的增加而上升。从这样一个尸检系列中所能确定的情况来看，淋巴结纤维化有可能易导致肺实质矽肺的发生。
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