聚氯乙烯配料工人呼气峰值流速的日变化
Diurnal variation in peak expiratory flow rate among polyvinylchloride compounding workers.
作者信息
Lee H S, Ng T P, Ng Y L, Phoon W H
机构信息
Department of Industrial Health, Ministry of Labour, Singapore.
出版信息
Br J Ind Med. 1991 Apr;48(4):275-8.
The diurnal variation in peak expiratory flow rate (PEFR) was studied in 24 mixers and 24 non-mixers in three polyvinylchloride (PVC) compounding plants and 24 non-PVC controls from a marine police workshop. The three groups (all men) were matched for age, race, and smoking. The mean respirable dust concentration (essentially PVC dust) was 1.6 mg/m3 for mixers and 0.4 mg/m3 for nonmixers. The mean diurnal variation in PEFR of the mixers was 6.5%. This was significantly higher than the 4.8% for non-mixers and 4.3% for the non-PVC controls. Six mixers had a diurnal variation of more than 15% on at least one day compared with none among the other two groups. Twenty nine per cent of mixers complained of wheezing compared with 4% of non-mixers and none among non-PVC workers. These differences were significant. Forced expiratory volume in one second (FEV1) for the mixers was 10% below the predicted values whereas that of non-PVC workers was 2% below predicted values. The study indicates a significant acute airway constriction from occupational exposure to PVC dust.
在三家聚氯乙烯（PVC）复合厂的24名混料工人和24名非混料工人，以及一名海上警察车间的24名非PVC对照人员中，研究了呼气峰值流速（PEFR）的昼夜变化。这三组人员（均为男性）在年龄、种族和吸烟方面进行了匹配。混料工人的平均可吸入粉尘浓度（主要是PVC粉尘）为1.6毫克/立方米，非混料工人为0.4毫克/立方米。混料工人PEFR的平均昼夜变化为6.5%。这显著高于非混料工人的4.8%和非PVC对照人员的4.3%。六名混料工人在至少一天内的昼夜变化超过15%，而其他两组中无人如此。29%的混料工人抱怨有喘息，相比之下，非混料工人为4%，非PVC工人则无人抱怨。这些差异具有显著性。混料工人的一秒用力呼气量（FEV1）比预测值低10%，而非PVC工人比预测值低2%。该研究表明，职业性接触PVC粉尘会导致明显的急性气道收缩。
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