Hair L S, Rogers J D, Chadburn A, Sisti M B, Knowles D M, Powers J M
Department of Pathology, Neuropathology and Hematopathology, Columbia Presbyterian Hospital, College of Physicians and Surgeons, New York, New York 10032.
Cancer. 1991 Jun 1;67(11):2931-4. doi: 10.1002/1097-0142(19910601)67:11<2931::aid-cncr2820671137>3.0.co;2-e.
Intracerebral involvement of Hodgkin's disease (HD) is rarely described, with only 42 cases in the literature. Since the outbreak of the acquired immune deficiency syndrome (AIDS) epidemic, there has been an increasing number of human immunodeficiency virus (HIV)-infected (HIV+) persons who have diffuse non-Hodgkin's lymphoma and, more recently, atypical aggressive HD. The authors report the case of a patient with a history of intravenous drug abuse (IVDA) and Stage IVB HD who, after a drug-induced clinical remission, had intracerebral mixed-cellularity HD. This appears to be the first report of intracerebral HD in a person who is HIV+.
霍奇金淋巴瘤（HD）的脑内累及情况鲜有报道，文献中仅有42例。自获得性免疫缺陷综合征（AIDS）流行以来，感染人类免疫缺陷病毒（HIV）的（HIV+）人群中弥漫性非霍奇金淋巴瘤以及最近出现的非典型侵袭性HD的病例不断增加。作者报告了1例有静脉药物滥用（IVDA）史且处于IVB期HD的患者，在药物诱导的临床缓解后发生脑内混合细胞型HD。这似乎是HIV+人群中脑内HD的首例报告。
