卵巢癌患者DNA指数、p62c-myc与临床病理状态的多变量分析。
Multivariate analyses of DNA index, p62c-myc, and clinicopathological status of patients with ovarian cancer.
作者信息
Curling M, Stenning S, Hudson C N, Watson J V
机构信息
Clinical Oncology Unit, Medical School, Cambridge, UK.
出版信息
J Clin Pathol. 1998 Jun;51(6):455-61. doi: 10.1136/jcp.51.6.455.
AIM
To determine if either DNA index or p62c-myc is an independent prognostic variable in ovarian cancer.
METHODS
Multivariate and univariate analyses of the relation between DNA index, p62c-myc, FIGO stage, histological type, tumour grade, completeness of surgery, and patient survival in ovarian cancer were examined.
RESULTS
Multivariate analysis showed significant association of survival only with stage and grade. There was no relation between survival and DNA index.
CONCLUSIONS
DNA index is not an independent prognostic variable in ovarian cancer.
目的
确定DNA指数或p62c-myc是否为卵巢癌的独立预后变量。
方法
对DNA指数、p62c-myc、国际妇产科联盟（FIGO）分期、组织学类型、肿瘤分级、手术完整性与卵巢癌患者生存率之间的关系进行多因素和单因素分析。
结果
多因素分析显示，仅分期和分级与生存率有显著相关性。生存率与DNA指数之间无相关性。
结论
DNA指数不是卵巢癌的独立预后变量。
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