Wali N, Leguire L E, Rogers G L, Bremer D L
Ophthalmology Department, Children's Hospital, Columbus, Ohio.
Optom Vis Sci. 1991 Feb;68(2):81-7. doi: 10.1097/00006324-199102000-00001.
Contrast sensitivity functions (CSF's) were measured in the amblyopic and dominant eyes of 17 strabismic and 28 anisometropic children and in 19 similar age normal controls. A three-alternative forced-choice procedure was used to measure CSF's with the VCTS 6500. The results revealed reduced contrast sensitivity (CS) in both the amblyopic and dominant eyes of strabismic and anisometropic amblyopes compared to normal controls. Statistically significant intereye correlations of CS at each spatial frequency were found in all groups and in the presence of deep amblyopia, suggesting continued interocular interactions and binocularity. A separate longitudinal study of 7 of the amblyopes showed that, during the course of occlusion therapy, both the amblyopic and the dominant eyes improved in CSF. The results suggest that the amblyopic eye may influence CS in the dominant eye through interocular interactions. This process may serve to minimize CSF differences between the eyes and maximize binocular vision.
在17名斜视儿童和28名屈光参差儿童的弱视眼和优势眼中以及19名年龄相仿的正常对照者中测量了对比敏感度函数（CSF）。采用三选一强迫选择程序，使用VCTS 6500测量CSF。结果显示，与正常对照相比，斜视性弱视和屈光参差性弱视患者的弱视眼和优势眼的对比敏感度（CS）均降低。在所有组中以及存在重度弱视的情况下，在每个空间频率下CS的两眼间相关性具有统计学意义，这表明两眼间持续存在相互作用和双眼视功能。对7名弱视患者进行的一项单独纵向研究表明，在遮盖治疗过程中，弱视眼和优势眼的CSF均有所改善。结果表明，弱视眼可能通过两眼间相互作用影响优势眼的CS。这一过程可能有助于使两眼间的CSF差异最小化，并使双眼视力最大化。
