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非甾体抗炎药引起的上消化道症状患者的心理特征

Psychological profiles of patients with upper gastrointestinal symptomatology induced by non-steroidal anti-inflammatory drugs.

作者信息

Juby A, Davis P

机构信息

Department of Rheumatology, University of Alberta, Edmonton, Canada.

出版信息

Ann Rheum Dis. 1991 Apr;50(4):211-3. doi: 10.1136/ard.50.4.211.

Abstract

Eighty three patients with classical or definite rheumatoid arthritis taking non-steroidal anti-inflammatory drugs (NSAIDs) were studied in an attempt to determine whether a patient's personality and psychological profile might contribute to the development of NSAID induced gastrointestinal symptomatology. It was found that the personality profile of the group of 45 asymptomatic patients was similar to that of a previously reported control group. In contrast, the 37 patients with gastrointestinal symptoms attributed to NSAIDs had a significantly higher mean score for free floating anxiety, depression, and somatisation than controls, suggesting that a patient's personality may influence the development of NSAID induced gastric symptoms.

摘要

对83例正在服用非甾体抗炎药(NSAIDs)的典型或确诊类风湿性关节炎患者进行了研究,以确定患者的性格和心理状况是否可能导致非甾体抗炎药引起的胃肠道症状。结果发现,45例无症状患者的性格特征与先前报道的对照组相似。相比之下,37例因非甾体抗炎药导致胃肠道症状的患者在自由浮动焦虑、抑郁和躯体化方面的平均得分显著高于对照组,这表明患者的性格可能会影响非甾体抗炎药引起的胃部症状的发生。

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Epidemiology of nonsteroidal anti-inflammatory drug-associated gastrointestinal injury.非甾体抗炎药相关胃肠道损伤的流行病学
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本文引用的文献

1
The personality pattern of patients with chronic peptic ulcer. A case-control study.
Scand J Gastroenterol. 1983 Oct;18(7):945-50. doi: 10.3109/00365528309182120.
6
Toward an epidemiology of gastropathy associated with nonsteroidal antiinflammatory drug use.
Gastroenterology. 1989 Feb;96(2 Pt 2 Suppl):647-55. doi: 10.1016/s0016-5085(89)80061-7.
8
Silent peptic ulceration: deadly silence or golden silence?无症状消化性溃疡:致命的沉默还是宝贵的沉默?
Gastroenterology. 1989 Feb;96(2 Pt 2 Suppl):626-31. doi: 10.1016/s0016-5085(89)80058-7.

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