Juby A, Davis P
Department of Rheumatology, University of Alberta, Edmonton, Canada.
Ann Rheum Dis. 1991 Apr;50(4):211-3. doi: 10.1136/ard.50.4.211.
Eighty three patients with classical or definite rheumatoid arthritis taking non-steroidal anti-inflammatory drugs (NSAIDs) were studied in an attempt to determine whether a patient's personality and psychological profile might contribute to the development of NSAID induced gastrointestinal symptomatology. It was found that the personality profile of the group of 45 asymptomatic patients was similar to that of a previously reported control group. In contrast, the 37 patients with gastrointestinal symptoms attributed to NSAIDs had a significantly higher mean score for free floating anxiety, depression, and somatisation than controls, suggesting that a patient's personality may influence the development of NSAID induced gastric symptoms.
对83例正在服用非甾体抗炎药(NSAIDs)的典型或确诊类风湿性关节炎患者进行了研究,以确定患者的性格和心理状况是否可能导致非甾体抗炎药引起的胃肠道症状。结果发现,45例无症状患者的性格特征与先前报道的对照组相似。相比之下,37例因非甾体抗炎药导致胃肠道症状的患者在自由浮动焦虑、抑郁和躯体化方面的平均得分显著高于对照组,这表明患者的性格可能会影响非甾体抗炎药引起的胃部症状的发生。