Linker D T, Rossvoll O, Chapman J V, Angelsen B A
Department of Biomedical Engineering, University of Trondheim, Norway.
Br Heart J. 1991 Apr;65(4):201-3. doi: 10.1136/hrt.65.4.201.
Twenty nine patients (aged from three months to 37 years) with confirmed or suspected ventricular septal defects were studied separately by three examiners who used colour flow mapping and imaging, or continuous wave Doppler and imaging, or a combined reference examination. Colour flow mapping identified 19 of the 25 patients with a ventricular septal defect, continuous wave Doppler echocardiography identified 18, and the combined reference examination identified 24. Two of four patients without ventricular septal defect had a false positive result with colour flow mapping and none had a false positive result with continuous wave Doppler examination. During the reference examination continuous wave Doppler identified 24 patients with ventricular septal defects and colour flow mapping identified 23. In two patients a second ventricular septal defect was found by colour flow mapping, and confirmed by continuous wave Doppler. There was no significant difference in time to diagnosis between the two techniques. Colour flow mapping aids identification of multiple ventricular septal defects but is not faster and has lower specificity than continuous wave Doppler. A combination of the two techniques gave the highest sensitivity and specificity.
29例确诊或疑似室间隔缺损的患者（年龄从3个月至37岁）由三名检查者分别采用彩色血流图和成像、连续波多普勒和成像或联合参考检查进行研究。彩色血流图在25例室间隔缺损患者中识别出19例，连续波多普勒超声心动图识别出18例，联合参考检查识别出24例。4例无室间隔缺损的患者中有2例彩色血流图出现假阳性结果，连续波多普勒检查均无假阳性结果。在参考检查中，连续波多普勒识别出24例室间隔缺损患者，彩色血流图识别出23例。彩色血流图发现2例患者存在第二个室间隔缺损，并经连续波多普勒证实。两种技术在诊断时间上无显著差异。彩色血流图有助于识别多个室间隔缺损，但并不比连续波多普勒更快，且特异性较低。两种技术联合使用可获得最高的敏感性和特异性。
