Hatle L, Rokseth R
Acta Med Scand Suppl. 1981;645:47-56. doi: 10.1111/j.0954-6820.1981.tb02600.x.
The presence of ventricular septal defect can be diagnosed noninvasively by Doppler ultrasound. Care must be taken to distinguish between VSD and infundibular pulmonary stenosis. VSD was easily differentiated from other cardiac lesions. In 55% of the patients a pressure drop across the VDS, comparable to that present, could be calculated from maximal recorded. In the remaining patients velocity and pressure drop were underestimated, probably due to a too large angle between ultrasound beam and velocity. Pulmonary artery systolic pressure was correctly estimated from Pc-To interval and heart rate, and RPEP(RVET) indicated whether normal or raised diastolic pressure was present in most patients.
室间隔缺损的存在可通过多普勒超声进行无创诊断。必须注意区分室间隔缺损和漏斗部肺动脉狭窄。室间隔缺损很容易与其他心脏病变区分开来。在55%的患者中，可以根据最大记录值计算出与实际存在的跨室间隔缺损压差相当的压差。在其余患者中，速度和压差被低估，可能是由于超声束与速度之间的夹角过大。肺动脉收缩压可根据肺动脉瓣关闭至第二心音间隔（Pc-To）和心率正确估算，右室射血前期（RPEP）与右室射血时间（RVET）的比值可提示大多数患者舒张期压力是否正常或升高。
