在东京和旧金山之间进行为期三天的旅行后血浆皮质醇水平昼夜节律的恢复。

Recovery of circadian rhythm of plasma cortisol levels after a 3-day trip between Tokyo and San Francisco.

作者信息

Tajima N, Uematsu M, Asukata I, Yamamoto K, Sasaki M, Hokari M

机构信息

Flight Crew Medical Service Department, Japan Airlines, Tokyo.

出版信息

Aviat Space Environ Med. 1991 Apr;62(4):325-7.

PMID:2031634

Abstract

The objective of the present study is to investigate the change in the circadian rhythm of plasma cortisol levels following a 3-d trip and a westbound return flight from San Francisco (SFO) to Tokyo. Six healthy male students volunteered for the project. Plasma cortisol levels were monitored 4 times daily for 13 d during the experimental period. In Tokyo, the baseline pattern of cortisol concentrations showed the classical diurnal profile. During the 50-h stay in SFO, phase advancement of 8 h was observed for the initial 32 h. This was followed by a disturbance in the profile for the remaining 18-h period. After returning to Tokyo, the subjects exhibited the original diurnal pattern beginning Day 1. However, complete resynchronization was not apparent until Day 4 after the return.

摘要

本研究的目的是调查一次为期3天的旅行以及从旧金山（SFO）到东京的向西返程航班后血浆皮质醇水平昼夜节律的变化。六名健康男学生自愿参与该项目。在实验期间，每天监测血浆皮质醇水平4次，持续13天。在东京，皮质醇浓度的基线模式呈现出典型的昼夜分布。在旧金山停留的50小时内，最初32小时观察到相位提前8小时。随后在剩余的18小时内分布出现紊乱。回到东京后，受试者从第1天开始呈现出原来的昼夜模式。然而，直到返回后第4天才明显完全重新同步。