Cameron J, Stainer D W
Acta Microbiol Acad Sci Hung. 1977;24(3):195-205.
The present paper indicates a number of unresolved problems in the metabolism of Bordetella pertussis and in the standardization of pertussis vaccines. The use of chemically defined media should enable the metabolic problems to be clarified. The problems concerned with the control and standardization of vaccines can largely be resolved in the laboratory with the introduction of reference preparations but the question of the reactivity of vaccine remains for the future.
本文指出了百日咳博德特氏菌代谢及百日咳疫苗标准化方面的一些未解决问题。使用化学成分明确的培养基应能澄清代谢问题。随着参考制剂的引入，与疫苗控制和标准化相关的问题在很大程度上可在实验室得到解决，但疫苗反应性问题仍有待未来解决。
